bioRxivMicrobiologyPreprint
EMERGENCE OF OXA-48-LIKE CARBAPENEMASES IN CLINICAL ENTEROBACTERALES FROM GUATEMALA
C. J. Mazariegos, A. Quinto, A. Herrera, S. E. Barillas, L. R. Valenzuela, G. Ordonez, P. Sierra, C. Arevalo, C. Seah, R. G. Melano
Abstract
Five isolates (four Klebsiella pneumoniae and one Escherichia coli) displaying resistance to piperacillin/tazobactam and ertapenem and reduced susceptibility to imipenem were found positive for blaOXA-48-like genes (blaOXA-181 and blaOXA-232) carried on plasmids described previously. Although two K. pneumoniae recovered in 2020 were clonally related, the results suggest that blaOXA-48-like genes have been circulating in Guatemala since 2019. This is the first report of this type of carbapenemase in Central America.
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