Comparative analysis of muscle thickness, muscle percentage of subcutaneous tissue, and muscle luminance in skeletal muscles of limbs of normal children and children with limb disabilities due to cerebral palsy using ultrasound imaging

Abstract

BackgroundUltrasound imaging is increasingly utilized for musculoskeletal evaluation because it is cost-effective and non-invasive. This study aims to analyze the differences in muscle thickness, muscle percentage of subcutaneous tissue, and muscle luminance in children with limb disabilities due to cerebral palsy compared with typically developing children. MethodsThis cross-sectional study included 12 children aged 6-15 years, divided equally into two groups: children with physical disabilities due to cerebral palsy and healthy controls. Ultrasound imaging was used to measure muscle thickness, percentage of muscle in subcutaneous tissue, and muscle luminance in various muscle groups of the limbs. Statistical analyses were conducted using t-tests to compare the two groups. ResultsSignificant differences were observed in muscle thickness and percentage of muscle in subcutaneous tissue between the groups, particularly in the lower limbs. Muscle luminance did not exhibit consistent differences. These findings suggest a decreased muscle mass and altered composition in children with cerebral palsy, which may influence their physical function and mobility. ConclusionsOur results underscore the value of ultrasound in clinically assessing muscle properties in children with cerebral palsy. This modality offers a promising tool for evaluating muscle alterations and potentially guiding targeted interventions to improve mobility and quality of life in affected children.