Author

N. Nigam

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Pathology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

A. Hegde· 1 shared A. Hiwale· 1 shared B. Bernard· 1 shared B. Carter· 1 shared B. Dam· 1 shared C. Chen· 1 shared C. Jamora· 1 shared C. Sievers· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperPathology

A. Hegde

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Angiopoietin-like protein 2 mediates vasculopathy driven fibrogenesis in a mouse model of systemic sclerosis

D. Saha, S. Thannimangalath, N. Pincha, R. Kiran, A. Hegde, S. Kataria, B. Dam, A. Hiwale, V. Ravula, L. M. Rahulan, N. Nigam, N. Singh, V. Agarwal, P. K. Vemula, C. Jamora

This study identifies Angptl2 as a driver of fibrotic vasculopathy in a mouse model of SSc and shows that inhibiting its effects can reduce fibrogenesis.

bioRxiv · Oct 16, 2023Pathology

Epigenetic silencing by SMYD3 represses tumor intrinsic interferon response in HPV-negative squamous cell carcinoma of the head and neck.

N. Nigam, B. Bernard, S. Kim, K. Burkitt, D. Tsai, Y. Robbins, C. Sievers, C. T. Allen, R. L. Bennett, T. T. Tettey, B. Carter, R. Bao, L. Rinaldi, M. W. Lingen, H. Sater, , V. Saloura

This study identifies SMYD3 as an epigenetic regulator that suppresses the intrinsic interferon response in HPV-negative HNSCC, offering a potential strategy to enhance immunotherapy response.

bioRxiv · Nov 4, 2022 · PreprintCancer Biology

The contributions of extracellular matrix and sarcomere properties to passive muscle stiffness in cerebral palsy

R. N. Konno, N. Nigam, J. M. Wakeling, S. A. Ross

This study uses a 3D muscle model to isolate the effects of extracellular matrix and sarcomere changes on passive muscle stiffness in cerebral palsy.

bioRxiv · Jun 17, 2021Physiology