Domiziana Costamagna

This study examines adult stem cell fusion capacity in CP patients, finding higher fusion in Medial Gastrocnemius muscle compared to typically developing children, with reduced potency in Semitendinosus muscle.

This study shows that PGC-1α in myofibers increases myogenic progenitors and reduces adipogenesis, enhancing muscle regeneration.

This study uses DMD patient iPSCs to model cardiomyopathy, identifies NOX4 as a therapeutic target due to its role in ROS production, and shows interventions that reduce oxidative stress and improve cell survival.