bioRxivNeurosciencePreprint
Cortico-genetic mapping links individual brain maturity in youths to cognitive and psychiatric traits
Tobias KaufmanniD, Dennis van der MeeriD, Dag AlnæsiD, Oleksandr FreiiD, Olav Bjerkehagen SmelandiD, Ole A. AndreasseniD, Lars Tjelta WestlyeiD
Abstract
Neurodevelopmental trajectories are shaped by interactions between coordinated biological processes and individual experiences throughout ontogeny, yet the specific genetic and environmental impact on brain development is enigmatic. Here, we map the genetic architectures of cognitive traits and psychiatric disorders onto the brain, show that such canonical genetic maps are associated with individual normative patterns in youths, and provide evidence that trauma exposure and parental education may alter this relationship.
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