Orthographic deficits but typical visual perceptual processing in Chinese adults with reading disability

Abstract

Visual orthographic deficits have been reported as one of the core deficits in reading disability (RD), however, whether the deficits are orthographic-specific or domain general in all visual processing is still in debate. Hereby, we conducted an fMRI and an EEG study to examine visual orthographic deficits in Chinese adults with RD. In the fMRI study, we found that there was reduced brain activation in the left inferior temporal gyrus and right cuneus gyrus in orthographic processing (lexical minus perceptual), but not in visual perceptual processing (perceptual minus null) in adults with RD, suggesting orthographic-specific deficits. In the EEG study, adults with RD showed typical visual binding as indicated by intermodulation SSVEPs (steady-state visual-evoked potentials) for both real and pseudo characters, suggesting normal neural phase locking in the visual modality. These results consistently suggest orthographic specific deficits but normal visual perceptual processing in adults with RD, deepening our understanding of the underlying deficits associated with RD.