bioRxivNeurosciencePreprint
Modulation of white matter bundle connectivity in the presence of axonal truncation pathologies
Robert Elton SmithiD, Fernando CalamanteiD, Sanuji. I. GajamangeiD, Scott KolbeiD, Alan ConnellyiD
Abstract
Endpoint-to-endpoint fibre bundle connectivity estimated using spherical deconvolution & streamlines tractography in diffusion MRI may be excessive in the presence of pathologies that involve truncation of axons within the white matter. Here we propose a simple modification to an existing method that directly quantifies and corrects for this over-estimation.
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