Fang-Cheng F. Yeh

Cortical asymmetry and its developmental change have distinct relationships with brain connectivity

This study examines how cortical asymmetry and its developmental changes relate to brain connectivity across three cohorts from birth to 22 years.

Reproducibility of Diffusion, Shape, and Connectivity Metrics Across Scanners: Implications for Multi-Site Tractography

The paper evaluates the reproducibility of diffusion, shape, and connectivity metrics across scanners in multi-site tractography studies and finds shape metrics show the highest reproducibility.

Anatomical White Matter Tracts Span the Cortical Hierarchy to Support Cognitive Diversity

The paper shows that white matter tracts are positioned within the cortical hierarchy to support specific cognitive functions and connect regions with greater cognitive diversity.

A hierarchical framework for cortical and subcortical gray-matter parcellation across rodents, primates, and humans

The paper develops a hierarchical atlas for gray-matter parcellation across multiple species, validated through cross-species comparisons and connectivity analysis.

Mapping the spatiotemporal continuum of structural connectivity development across the human connectome in youth

The paper identifies a spatiotemporal continuum of structural connectivity development in youth, showing a shift from sensorimotor to association connectivity around age 15 and its links to cognition and psychopathology.

Tractometry-Based Quantification of Along-Tract White-Matter Hemispheric Asymmetry in Alzheimer's Disease

This paper introduces an asymmetry-aware tractometry framework to quantify left-right hemispheric asymmetries in white matter tracts and applies it to Alzheimer's Disease data to differentiate cognitive states.

White matter reflects the childhood exposome

This study links childhood environmental exposures to white matter structure in children, showing that advantaged environments correlate with larger white matter tracts and reduced orientation dispersion.

Directed connectomes across species reveal conserved and divergent pathways of neural signaling

The paper constructs directed connectomes across species using viral tracing and diffusion MRI to identify conserved and divergent neural pathways.

A sensorimotor-association axis of thalamocortical connection development

The paper shows thalamocortical connections develop along a sensorimotor-association gradient in youth, linking structural connectivity to cortical plasticity and environmental sensitivity.

An Open Resource: MR and light sheet microscopy stereotaxic atlas of the mouse brain

The paper creates a multimodal 3D mouse brain atlas using MR histology and light sheet microscopy, improving spatial resolution and enabling stereotaxic labeling of brain images.

Probabilistic Coverage of the Frontal Aslant Tract in Young Adults: Insights into Individual Variability, Lateralization, and Language Functions

This study examines individual variability and lateralization of the frontal aslant tract (FAT) in young adults using diffusion MRI, finding significant left lateralization and correlations with language function.

Direct interhemispheric cortical communication via thalamic commissures: a new white-matter pathway in the primate brain

The paper identifies thalamic commissures in primates, showing they connect cortex to contralateral thalamus and exist in both healthy and malformed human brains.

Short superficial white matter and aging: a longitudinal multi-site study of 1,293 subjects and 2,711 sessions

The paper analyzes longitudinal MRI data from 1,293 subjects to study age-related changes in superficial white matter microstructure and U-fiber volume and length.

Insights from the IronTract challenge: optimal methods for mapping brain pathways from multi-shell diffusion MRI

The paper evaluates tractography methods using a macaque dataset to determine optimal approaches for mapping brain pathways from multi-shell diffusion MRI.

Aging and white matter microstructure and macrostructure: a longitudinal multi-site diffusion MRI study of 1,184 participants

This study analyzes diffusion MRI data from 1184 participants to quantify age-related changes in white matter microstructure and macrostructure, finding that macrostructural features show more heterogeneous age-related decline.

HiDiver: A Suite of Methods to Merge Magnetic Resonance Histology, Light Sheet Microscopy, and Complete Brain Delineations

HiDiver integrates multimodal brain imaging data to enable 3D quantitative analysis of brain structure and function in mice.

Multimodal Magnetic Resonance Histology and Light Sheet Imaging for Quantitative Neurogenetics of the Mouse

The paper develops a combined MRI and light sheet imaging approach to generate high-resolution brain phenotypes for neurogenetic studies in mice.

In vivo Restricted-Diffusion Imaging (RDI) is sensitive to differences in axonal density in typical children and adults

This study shows that RDI accurately maps axonal density in adults and children compared to other diffusion imaging methods.

Tractography dissection variability: what happens when 42 groups dissect 14 white matter bundles on the same dataset?

This study evaluates variability in white matter bundle segmentation across 42 groups using the same dataset, finding protocol variability exceeds other sources of inconsistency.

Fiber tractography bundle segmentation depends on scanner effects, vendor effects, acquisition resolution, diffusion sampling scheme, diffusion sensitization, and bundle segmentation workflow

This study evaluates how scanner, vendor, resolution, diffusion scheme, and segmentation workflow variations affect diffusion tractography bundle segmentation results.

Integrating across neuroimaging modalities boosts prediction accuracy of cognitive ability

The paper improves prediction of cognitive abilities by integrating multiple neuroimaging modalities using machine learning, achieving a 1-4% increase in variance explained compared to single-modality approaches.

Redundancy Circuits of the Commissural Pathways in Human and Rhesus Macaque Brains

The paper identifies and compares three redundancy circuits in commissural pathways between human and rhesus macaque brains, finding reduced volumes in humans that support a redundancy-efficiency tradeoff.

White matter neuroanatomical predictors of aphasic verb retrieval

This study identifies white matter tracts associated with verb retrieval in aphasia, finding that motor-related projection pathways are more strongly linked than traditional dual-stream language tracts.

The Impact of Edema and Fiber Crossing on Diffusion MRI Metrics: DBSI vs. Diffusion ODF

This study compares diffusion MRI metrics in simulated edema and fiber crossing, finding DBSI provides more accurate diffusivity and angle estimates than DTI and other methods.

QSIPrep: An integrative platform for preprocessing and reconstructing diffusion MRI

QSIPrep is a software platform for preprocessing diffusion MRI data that supports multiple sampling schemes and ensures reproducibility through standardized workflows and quality measures.

Shape Analysis of the Human Association Pathways

This study applies shape analysis to diffusion MRI tractography data to quantify and compare structural features of human association pathways, revealing lateralization patterns and between-subject variation.

Differential Tractography as a Track-Based Biomarker for Neuronal Injury

This paper introduces differential tractography to detect neuronal injury by comparing repeat MRI scans and shows its clinical relevance in multiple neurological conditions.

Machine learning versus logistic regression methods for 2-year mortality prognostication in a small, heterogeneous glioma database

The paper compares machine learning and logistic regression for predicting 2-year mortality in a small glioma dataset, finding similar performance between ML methods and logistic regression.

Automatic Removal of False Connections in Diffusion MRI Tractography Using Topology-Informed Pruning (TIP)

This paper introduces TIP, a method to remove false connections in diffusion MRI tractography, improving accuracy by 11.93% in single-shell schemes and 3.47% in grid schemes.

Population-Averaged Atlas of the Macroscale Human Structural Connectome and Its Network Topology

The paper creates a population-averaged atlas of the human structural connectome using diffusion MRI data, revealing network topology features like small-worldness and hub structures.