Experience dependent plasticity of higher visual cortical areas in the mouse

Introduction ABSTRACT Introduction Materials and Methods Results Discussion CRediT authorship contribution... Funding References Since the pioneering work by Hubel and Wiesel on cats and monkeys in the 1960s and 1970s (Wiesel and Hubel, 1963; Hubel et al., 1977) ocular dominance (OD) plasticity has become one of the classic paradigms for the study of experience-dependent brain plasticity. Occluding one eye by monocular deprivation (MD) shifts responses of visual cortical neurons towards the open eye, in particular during a critical period early in life Hubel Wiesel (Hubel and Wiesel, 1970; Olson and Freeman, 1978). It also results in a substantial loss of visual acuity in the deprived eye ( ...