Thomas C. Brown

This study shows that aggrecan in excitatory neurons, not perineuronal nets, limits visual plasticity by closing the critical period in adult mice.

The paper shows that neuronal tuning instability is greater in juvenile mice and adult ngr1 mutant mice during critical period plasticity.

This study shows that microglia are not required for experience-dependent refinement of visual circuitry in mice.

This study shows that monocular deprivation during the critical period changes neuronal tuning and visual circuit composition in mice by altering responsive neurons and recruiting neurons with similar tuning properties.