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BioinformaticsGenomicsPeer-reviewed journal article

miqoGraph : Fitting admixture graphs using mixed-integer quadratic optimization

Julia YaniD, Nick J. PattersoniD, Vagheesh M. NarasimhaniD

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Citations
5
FWCI
0.73
Field percentile
top 31%

Abstract

Admixture graphs represent the genetic relationship between a set of populations through splits, drift and admixture. In this paper we present the Julia package miqoGraph, which uses mixed-integer quadratic optimization to fit topology, drift lengths, and admixture proportions simultaneously. Inference of topology is particularly powerful, with integer optimization automating what is usually an arduous manual process.\n\nAvailabilityhttps://github.com/juliayyan/PhylogeneticTrees.jl\n\nContactjyyan@mit.edu

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