Author

Chang Lei

Fudan UniversityORCID 0009-0006-1261-9101Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:whole-genome sequencing· 2 Approach:deep learning· 1 Organism:human· 1 Research Focus:software / tool· 1 Approach:statistical model· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Shuhua XuiD· 2 shared Baonan WangiD· 1 shared Dongsheng LuiD· 1 shared Huanyu Lin· 1 shared Kai Yuan· 1 shared Shuanghui CheniD· 1 shared Weishun ZengiD· 1 shared Xiaohan ZhaoiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersBioinformatics

Shuhua XuORCID

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2 papers

Recent·Most cited

BioinformaticsbioRxivPreprintMay 6, 2026

ArchaicSeeker 3.0: A deep-learning framework for scalable, haplotype-resolved inference of archaic introgression

Baonan Wang, Chang Lei, Huanyu Lin…·Shuhua Xu

ArchaicSeeker 3.0 detects archaic introgression using deep learning, outperforming existing methods in precision, recall, and F1 score across diverse genomic contexts and population sizes.

DOI 10.64898/2026.05.05.722798

humanwhole-genome sequencing

𝕏 PostBluesky

GeneticsGenome Biology and EvolutionPeer-reviewedNov 1, 2024

AncestryPainter 2.0: Visualizing ancestry composition and admixture history graph

Shuanghui Chen, Chang Lei, Xiaohan Zhao…·Shuhua Xu

AncestryPainter 2.0 visualizes ancestry composition and admixture history using improved graphical and statistical modules.

14 citations

whole-genome sequencingstatistical model

𝕏 PostBluesky