THE PATTERN OF BACTERIA AND ITS RESISTANCE ON ADULT SEPSIS PATIENT AT Dr. MOEWARDI GENERAL HOSPITAL, INDONESIA
Andika Dwi Mahendra, M Kuswandi Tirtodiharjo, Ika Trisharyanti D Kusuma
Abstract
BackgroundSepsis incidence which related with morbidity and mortality, is globally increasing. Sepsis occurs because of severe infections. Sepsis has life-threatening potential with organ disfungction complication, septic shock, and death. Alteration of resistance pattern always change at certain period. The aim of the study is to investigate the bacteria pattern and its resistance from adult sepsis patient at Dr. Moewardi Regional General Hospital.\n\nMethodsIsolated bacteria from adult sepsis patients blood at Dr. Moewardi Regional General Hospital. 7 bacteria isolates were taken from blood of adult sepsis patient (September - October 2014) and 46 bacteria isolates of secondary data (January - March 2014) at Dr. Moewardi Regional General Hospital. Bacteria isolation was performed based on standard Laboratory of Microbiology of Dr. Moewardi Regional General Hospital. 7 bacteria isolates were tested by using disc diffusion antibiotic on Mueller Hinton and coupled by 46 secondary data.\n\nResultsThe bacteria pattern from adult sepsis patients were Staphylococcus haemolyticus (15,09%), Staphylococcus hominis (15,09%), Escherichia coli (13,21%), and Acinetobacter baumannii (11,32%). Resistance pattern of bacteria on adult sepsis with level of resistant more than 50% as Staphylococcus haemolyticus (ciprofloxacin, erythromycin, levofloxacin, moxifloxacin, and gentamicin), Escherichia coli (gentamicin, ciprofloxacin, and levofloxacin), and Acinetobacter baumannii (gentamicin, ciprofloxacin, levofloxacin, and ceftazidime)\n\nConclutionsBased on this research, revealed that the most common bacteria caused sepsis was Gram negative about 64,64% of all bacteria on sepsis patient. The most frequent cause of sepsis was Staphylococcus hominis, Staphylococcus haemolyticus, and Escherichia coli.
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