Cortical tracking of natural speech by children with developmental language disorder (DLD): An EEG speech decoding investigation

Abstract

The sensory/neural Temporal Sampling (TS) theory of developmental language disorder (DLD) is based on the sensory and linguistic impairments in rhythm processing that are found in children with both developmental dyslexia (DD) and DLD. These sensory/linguistic impairments include decreased sensitivity to amplitude rise times (ARTs, the sensory triggers related to automatic cortical speech tracking), syllable stress patterns and speech rhythm. At the neural level TS theory predicts impairments in the cortical tracking of different rates of amplitude modulation (AM) in the speech signal <10Hz. To date, the accuracy of low-frequency cortical tracking in natural continuous speech has not been measured in children with DLD. Here, EEG was recorded during story listening from children with and without DLD aged around 9 years, and decoding analyses in the delta, theta and alpha (control) bands were carried out. EEG power was computed in the delta, theta and gamma bands, and phase-amplitude coupling and phase-phase coupling (PAC, PPC) were also computed between bands. Whole-brain analyses showed that the accuracy of low-frequency decoding (delta, theta) did not differ between groups. However, region-specific analyses revealed significantly reduced delta-band speech tracking in the right temporal cortex in the children with DLD. PAC and PPC dynamics did not differ between groups. The data suggest that low-frequency cortical tracking impairments in DLD may be spatially constrained to the right hemisphere rather than globally present as in DD. The data are discussed using TS theory. HighlightsO_LICortical tracking of natural speech is measured in children with and without DLD C_LIO_LIDelta-band tracking is impaired in right temporal regions in children with DLD C_LIO_LICross-frequency coupling dynamics (PAC, PPC) did not differ between groups C_LI