bioRxivPhysiologyPreprint
Mesenchymal stem cell-derived extracellular vesicles alleviate imiquimod-induced psoriasis symptoms in a mouse disease model
Yi YuaniD, Yu YaniD, Guowu LiuiD, Chuang Cui, Yanhua Zhai, Xinjun HeiD, Ke XuiD
Abstract
Psoriasis is an immune mediated, chronic inflammatory skin disease. Mesenchymal stem cell-derived extracellular vesicles (MSC-EVs) have inherent immunomodulatory potency from their parental cells, the mesenchymal stem cells (MSCs). In this study, we revealed the application potential of MSC-EVs to alleviate psoriatic symptoms in imiquimod-induced psoriasis mouse model.
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