bioRxivCell BiologyPreprint
Generation of a human Tropomyosin 1 knockout iPSC line
M. B. Wilken, J. A. Maguire, L. V. Dungan, A. Gagne, C. Osorio-Quintero, E. A. Waxman, S. T. Chou, P. Gadue, D. L. French, C. S. Thom
Abstract
The CHOPWT17_TPM1KOc28 iPSC line was generated to interrogate the functions of Tropomyosin 1 (TPM1) in primary human cell development. This line was reprogrammed from a previously published wild type control iPSC line.
Reproducibility ledger
Nobody has reported trying to reproduce this paper yet. Did you replicate an experiment or run the code? Your report saves the next lab a week.
Sign in to file a reproducibility report.
Related papers
- Generation and characterization of a patient-specific human induced pluripotent stem cell line from a Skogholt syndrome patient (ASCFi003-A)
Weronika Przybyła, Swapnil Gupta, … Kulbhushan Sharma·bioRxiv·Aug 31, 2026
- Tropomyosin 1 deficiency facilitates cell state transitions and enhances hemogenic endothelial cell specification during hematopoiesis
M. Wilken, G. Fonar, … C. S. Thom·bioRxiv·Sep 1, 2023
- Modeling ATN1 mutations in human iPSCs reveals early developmental roles of atrophin-1
Emilia Kozlowska, Natalia Ziojla, … Agnieszka Fiszer·bioRxiv·Nov 2, 2026
- Generation of human induced trophoblast stem cells
G. CASTEL, D. MEISTERMANN, … L. DAVID·bioRxiv·Sep 15, 2020
- Derivation of human post-mitotic cardiomyocytes from tetraploid iPSCs
Ittetsu Nakajima, Mitsuyoshi Shimane, … Yuichiro Miyaoka·Communications BiologyPeer-reviewed·Aug 17, 2026
- Development of a Stable Human iPSC Line from Peripheral Blood: A Control Resource for Disease Modeling
Surajit Malakar, Vasanth Thamodaran, … Parimal Kumar Das·bioRxiv·Aug 21, 2025