Author

C. S. Thom

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 4 Research Focus:cell type annotation· 3 Research Focus:cell signaling & trafficking· 2 Organism:mouse· 2 Assay:proteomics· 2 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1

Frequent Co-Authors

A. Gagne· 2 shared J. A. Maguire· 2 shared P. Gadue· 2 shared A. Freiwan· 1 shared C. M. Lechauve· 1 shared C. Nations· 1 shared C. Osorio-Quintero· 1 shared D. French· 1 shared

Activity by Year

2018-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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2 shared papersCell Biology

A. Gagne

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Author profile →

4 papers

Recent·Most cited

Quantitative label free mass spectrometry reveals content and signaling differences between neonatal and adult platelets

C. S. Thom, P. Davenport, H. Fazelinia, Z.-J. Liu, H. Zhang, H. Ding, J. Roof, L. A. Spruce, H. Ischiropoulos, M. Sola-Visner

This study compares the proteome and phosphoproteome of neonatal and adult platelets, identifying significant differences in protein content and phosphorylation that suggest developmental variations in immune function and activation potential.

bioRxiv · Sep 13, 2023 · PreprintCell Biology

Tropomyosin 1 deficiency facilitates cell state transitions and enhances hemogenic endothelial cell specification during hematopoiesis

M. Wilken, G. Fonar, C. Nations, G. Pavani, J. Gariffalou, J. Tober, L. F. Bennett, J. A. Maguire, A. Gagne, N. Okoli, P. Gadue, S. Chou, N. A. Speck, D. French, C. S. Thom

This study shows TPM1 deficiency promotes cell state transitions and enhances hemogenic endothelial cell specification during hematopoiesis in both human and mouse models.

bioRxiv · Sep 1, 2023Cell Biology

Generation of a human Tropomyosin 1 knockout iPSC line

M. B. Wilken, J. A. Maguire, L. V. Dungan, A. Gagne, C. Osorio-Quintero, E. A. Waxman, S. T. Chou, P. Gadue, D. L. French, C. S. Thom

The paper generates a human Tropomyosin 1 knockout iPSC line to study its role in primary human cell development.

bioRxiv · May 3, 2023 · PreprintCell Biology

Unc 51-like autophagy-activating kinase (ULK1) mediates clearance of free {alpha}-globin in {beta}-thalassemia

C. M. Lechauve, J. Keith, E. Khandros, S. Fowler, K. Mayberry, A. Freiwan, C. S. Thom, P. Delbini, E. Boada Romero, J. Zhang, I. Motta, H. Tillman, M. D. Cappellini, M. Kundu, M. J. Weiss

Rapamycin alleviates β-thalassemia by stimulating ULK1-dependent autophagy of toxic free α-globin.

bioRxiv · Oct 26, 2018 · PreprintCell Biology