2D:4D and spatial abilities: From rats to humans

Nils C. J. Müller; Siobhan Frances Campbell; Mio Nonaka; T.M. Rost; Gordon Pipa; Boris N. Konrad; Axel Steiger; Michael Czisch; Guillén Fernández; Martin Dresler; Lisa Genzel

doi:10.1016/j.nlm.2018.04.012

NeuroscienceNeurobiology of Learning and MemoryApr 22, 2018

Peer-reviewed journal article

2D:4D and spatial abilities: From rats to humans

Nils C. J. Müller iD, Siobhan Frances Campbell, Mio Nonaka iD, T.M. Rost iD, Gordon Pipa iD, Boris N. Konrad iD, Axel Steiger iD, Michael Czisch iD, Guillén Fernández iD, Martin Dresler iD, Lisa Genzel iD

Abstract

Variance in spatial abilities are thought to be determined by in utero levels of testosterone and oestrogen, measurable in adults by the length ratio of the 2nd and 4th digit (2D:4D). We confirmed the relationship between 2D:4D and spatial performance using rats in two different tasks (paired-associate task and watermaze) and replicated this in humans. We further clarified anatomical and functional brain correlates of the association between 2D:4D and spatial performance in humans.

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