Integrated Collection of Stem Cell Bank data, a data portal for standardized stem cell information

Ying Chen; Kunie Sakurai; Sumihiro Maeda; Tohru Masui; Hideyuki Okano; Johannes Dewender; Stefanie Seltmann; Armin Kurtz; Hiroshi Masuya; Yukio Nakamura; Michael Sheldon; Juliane Schneider; Glyn Nigel Stacey; Yulia Panina; Wataru Fujibuchi

doi:10.1016/j.stemcr.2021.02.014

BioinformaticsStem Cell ReportsMar 19, 2021

Peer-reviewed journal article

Integrated Collection of Stem Cell Bank data, a data portal for standardized stem cell information

Ying Chen iD, Kunie Sakurai, Sumihiro Maeda iD, Tohru Masui, Hideyuki Okano iD, Johannes Dewender iD, Stefanie Seltmann iD, Armin Kurtz iD, Hiroshi Masuya iD, Yukio Nakamura iD, Michael Sheldon iD, Juliane Schneider iD, Glyn Nigel Stacey iD, Yulia Panina iD, Wataru Fujibuchi iD

Abstract

The last decade has witnessed an extremely rapid increase in the number of newly established stem cell lines. However, due to the lack of a standardized format, data exchange among stem cell line resources has been challenging, and no system can search all stem cell lines across resources worldwide. To solve this problem, we have developed Integrated Collection of Stem Cell Bank data (ICSCB) (http://icscb.stemcellinformatics.org/), the largest database search portal for stem cell line information, based on the standardized data items and terms of the MIACARM framework. Currently, ICSCB can retrieve >16,000 cell lines from four major data resources in Europe, Japan, and the United States. ICSCB is automatically updated to provide the latest cell line information, and its integrative search helps users collect cell line information for over 1,000 diseases including many rare diseases worldwide, which has been a formidable task, thereby distinguishing itself from other database search portals.

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