The olfactory-based neurofeedback of the EEG alpha rhythm

Abstract

Neurofeedback (NFB) is a form of biofeedback that enables subjects to monitor and control their own brain activity. To communicate with the subject, modern NFB training methodologies utilize various signaling mechanisms, typically visual and/or auditory stimuli. Olfaction has not been explored yet as a way to deliver NFB. Here we developed an olfactory-based NFB system based on electroencephalographic (EEG) recordings in human participants. The system incorporates an EEG recording apparatus, a custom olfactory display for the automated delivery of Sniffin Sticks, and a Python application for the conversion of EEG rhythms into NFB signals and controlling behavioral tasks. We tested occipital alpha rhythm as the source of NFB. Fifteen healthy participants were randomly assigned to three groups: olfactory neurofeedback, auditory NFB, and mock-olfactory NFB. NFB training resulted in an increase of alpha power in the true NFB groups, but not in the mock NFB group where the alpha power decreased, probably because of fatigue and drowsiness. Based on these results, we conclude that olfactory NFB is feasible, and lay out a framework for its future development.