ShinyGO: a graphical enrichment tool for animals and plants

Abstract

MotivationGene lists are routinely produced from various genome-wide studies. Enrichment analysis can link these gene lists with underlying molecular pathways by using functional categories such as gene ontology (GO).\n\nResultsTo complement existing tools, we developed ShinyGO with several features: (1) large annotation database from GO and many other sources for over 200 plant and animal species, (2) graphical visualization of enrichment results and gene characteristics, and (3) application program interface (API) access to KEGG and STRING for the retrieval of pathway diagrams and protein-protein interaction networks. ShinyGO is an intuitive, graphical web application that can help researchers gain actionable insights from gene lists.\n\nAvailabilityhttp://ge-lab.org/go/\n\nContactgexijin@gmail.com\n\nSupplementary informationSupplementary data are available at Bioinformatics online.