Kaikun Xu

Targeting THOC2-Mediated mRNA Export Induces PARP Inhibitor Vulnerability in DNA Repair-Competent Hepatocellular Carcinoma

This study identifies THOC2 as a regulator of DNA repair and growth in HCC, showing that targeting THOC2 enhances PARPi efficacy by disrupting mRNA export of DDR genes.

MolSpecFlow: Mass-Constrained Hybrid Flow Matching for Joint Molecular-Spectral Analysis

MolSpecFlow bridges the gap between molecules and mass spectra using a hybrid flow matching model, achieving state-of-the-art results in de novo generation and spectral simulation.

EnrichMiner: a biologist-oriented web server for mining biological insights from functional enrichment analysis results

EnrichMiner provides a web server to help researchers explore and refine functional enrichment analysis results by removing redundancy and selecting representative terms.

PANDA: A comprehensive and flexible tool for proteomics data quantitative analysis

PANDA is a proteomics data quantification tool that offers higher accuracy and precision than MaxQuant with reduced computation time, supporting both label-free and labeled quantification.