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GeneticsBioinformatics
Peer-reviewed journal article

biMM: Efficient estimation of genetic variances andcovariances for cohorts with high-dimensional phenotype measurements

Matti PirineniD, Christian BenneriD, Pekka MarttineniD, Marjo‐Riitta JärveliniD, Manuel A. RivasiD, Samuli RipattiiD

Abstract

Genetic research utilizes a decomposition of trait variances and covariances into genetic and environmental parts. Our software package biMM is a computationally efficient implementation of a bivariate linear mixed model for settings where hundreds of traits have been measured on partially overlapping sets of individuals.\n\nAvailabilityImplementation in R freely available at www.iki.fi/mpirinen.

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02 /Specification & Classification

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