Yue Wu

The paper quantifies similarity in causal effects across local ancestries in admixed individuals and finds high genetic correlation (radmix=0.95) within individuals.

The paper introduces SCORE, a scalable and accurate method for estimating genetic correlation in large datasets, achieving higher precision than existing methods.

The paper introduces an efficient algorithm for variance components analysis, enabling rapid estimation of hundreds of variance components across large genomic datasets and demonstrating its utility in heritability estimation and functional annotation partitioning.

This paper introduces a method to accurately estimate SNP-heritability from large biobank data without assuming genetic architecture, showing existing methods can be off by up to 30%.

The paper introduces a scalable algorithm for estimating SNP heritability in large datasets, achieving efficient computation on biobank-scale data.

This paper shows that two types of imputation methods in GWAS are statistically equivalent and introduces an improved method that maintains power without variance re-weighting.