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BioinformaticsScientific Reports
Peer-reviewed journal article

Gene annotation bias impedes biomedical research

Winston A. HaynesiD, Aurelie TomczakiD, Purvesh KhatriiD

Abstract

1We found tremendous inequality across gene and protein annotation resources. We observe that this bias leads biomedical researchers to focus on richly annotated genes instead of those with the strongest molecular data. We advocate for researchers to reduce these biases by pursuing data-driven hypotheses.

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