Stochastic analysis of optimal production of infectious progeny in Chlamydia

Abstract

Recent data collected on the Chlamydia Trachomatis life cycle show an initial period of no RB-to-EB conversion. This and other features of the observed bacterial life cycle are postulated to be consequences of the bacterias drive for Darwinian survival. Stochastic optimal control models formulated herein in fact lead to an initial conversion holiday that support this proposition.