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MicrobiologybioRxiv
Preprint

Orfamide-A-mediated bacterial-algal interactions involve specific Ca2+ signalling pathways

Y. Hou, Y. Bando, D. Carrasco Flores, V. S. Hotter, B. Schiweck, H.-D. Arndt, M. Mittag

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Abstract

The antagonistic bacterium Pseudomonas protegens secretes the cyclic lipopeptide orfamide A, which triggers a Ca2+ signal, causing the deflagellation of the green microalga Chlamydomonas reinhardtii. By investigating targeted synthetic orfamide A variants and inhibitors, we found that at least two Ca2+-signalling pathways and TRP channels are involved in this response.

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