bioRxivMicrobiology
Evolutionary dynamics of carbapenem-resistant Acinetobacter baumannii circulating in Chilean hospitals
A. Opazo-Capurro, I. San Martin, M. Quezada-Aguiluz, F. Morales, M. Dominguez-Yevenes, C. Lima, F. Esposito, L. T. Cerdeira, H. M. Bello-Toledo, N. Lincopan, G. E. Gonzalez-Rocha
Abstract
We analyze the evolutionary dynamics of ninety carbapenem-resistant Acinetobacter baumannii (CRAB) isolates collected between 1990 and 2015 in Chile. CRAB were identified at first in an isolate collected in 2005, which harbored the ISAba1-blaOXA-69 arrangement. Later, OXA-58- and OXA-23-producing A. baumannii strains emerged in 2007 and 2009, respectively. This phenomenon was associated with variations in the epidemiology of OXA-type carbapenemases, linked to nosocomial lineages belonging to ST109 (CC1), ST162 (CC79), ST15 (CC15) and ST318 (CC15).
- organism: bacteria (other)
- research focus: host-pathogen & immune response
- approach: experimental assay
Reproducibility ledger
Nobody has reported trying to reproduce this paper yet. Did you replicate an experiment or run the code? Your report saves the next lab a week.
Sign in to file a reproducibility report.
Related papers
- Molecular epidemiology and clone transmission of carbapenem-resistant Acinetobacter baumannii in ICU rooms
Xiufeng Zhang, Fangping Li, … Zhenling Zeng·Frontiers in Cellular and Infection MicrobiologyPeer-reviewed·Feb 26, 2021
- Molecular Characterization of Carbapenem-Resistant Acinetobacter baumannii Clinical Isolates from Egyptian Patients
R. M. Hassan, S. T. Salem, … Sherifa T Salem, Saly Ismail Mostafa Hassan, Yasmine S Elkholy, Reem M Hassan·bioRxiv·Aug 24, 2020
- Molecular dissection of Carbapenem-resistant Acinetobacter baumannii circulating in Indian hospitals usingWhole Genome Sequencing
Steffimole Rose, Varun Shamanna, … K L Ravikumar·bioRxiv·Jul 30, 2021
- Outbreak of a carbapenem-resistant XDR Acinetobacter baumannii belonging to the International Clone II (IC2) in a clinical setting in Brazil, 2022
Érica Lourenço da Fonseca, Sergio Mascarenhas Morgado, … Ana Carolina Paulo Vicente·medRxiv·May 12, 2023
- Molecular epidemiology of carbapenemase-producing Acinetobacter spp. from Israel, 2001-2006: earliest report of blaNDM predating the oldest known blaNDM-positive strains
F. Grenier, V. Baby, … L.-P. Haraoui·bioRxiv·Jun 3, 2022
- Carbapenem-Resistant Acinetobacter baumannii in US hospitals: diversification of circulating lineages and antimicrobial resistance
A. V. Iovleva, M. M. Mustapha, … Y. Doi·bioRxiv·Sep 21, 2021