F. Esposito

Cytosolic and mitochondrial translation elongation are coordinated through the molecular chaperone TRAP1 for the synthesis and import of mitochondrial proteins

The paper identifies TRAP1's role in coordinating cytosolic and mitochondrial translation elongation for mitochondrial protein synthesis and import, revealing a feedback loop between protein synthesis and energy metabolism in cancer cells.

Nirmatrelvir treatment blunts the development of antiviral adaptive immune responses in SARS-CoV-2 infected mice

This study shows that nirmatrelvir treatment in SARS-CoV-2 infected mice reduces antibody and T cell responses, leading to weaker memory cell recruitment upon secondary challenge.

Area per player in small-sided games to replicate the external load and estimated physiological match demands in elite soccer players

This study determines the area-per-player in small-sided games with and without goalkeeper needed to replicate match demands in elite soccer players, finding larger areas are required for high-intensity activities.

Evolutionary dynamics of carbapenem-resistant Acinetobacter baumannii circulating in Chilean hospitals

The paper tracks the emergence and spread of carbapenem-resistant Acinetobacter baumannii strains in Chilean hospitals between 1990 and 2015, identifying key genetic changes and lineage associations.

Yersiniabactin, Colibactin and Wider Resistome Contribute to Enhanced Virulence and Persistence of KPC-2-Producing Klebsiella pneumoniae CG258 in South America

This study identifies yersiniabactin, colibactin, and an expanded resistome as factors contributing to the enhanced virulence and persistence of KPC-2-producing K. pneumoniae CG258 in South America.