Modeling of HIV-1 prophylactic efficacy and toxicity with islatravir shows non-superiority for oral dosing, but promise as a subdermal implant
H. Y. Kim, Lanxin Zhang, Craig W. Hendrix, Jessica Elizabeth Haberer, Max von Kleist
This paper models the efficacy and toxicity of islatravir as oral and subdermal PrEP, finding implants offer safer efficacy while oral dosing has toxicity risks.
bioRxiv · Apr 15, 2024 · PreprintSystems Biology