Specific non-myogenic mesenchymal cells contribute to rotator cuff tear fibrosis and myosteatosis revealing novel therapeutic options
Helen E. Rueckert, Anthony J. Mirando, Abigail P. Leinroth, Juliana Ibarra, Joe V. Chakkalakal, Matthew J. Hilton
This study identifies non-myogenic mesenchymal cells as contributors to rotator cuff tear fibrosis and myosteatosis and shows that targeting RET signaling can reduce fat infiltration.
bioRxiv · Feb 14, 2026 · PreprintCell Biology