SF3b inhibitors suppress proliferation of nonsmall cell lung cancer cells irrespective of EGFR mutation status
Wataru Fukagawa, Yuta Horita, Hiroyoshi Harada, Masayoshi Mori, Yusuke Murata, Kenji Ohe
The paper tests SF3b inhibitors on NSCLC cells with different EGFR statuses, finding growth suppression regardless of EGFR mutation, suggesting a mechanism independent of EGFR kinase activity.
bioRxiv · Oct 31, 2026 · PreprintMolecular Biology