Estrogen and related hormone effects

Inflammation reshapes epidermal and leukocyte differentiation resulting in altered glucocorticoid responsiveness

The paper investigates how inflammation alters cell type-specific glucocorticoid responsiveness through single-cell RNA sequencing in zebrafish.

Rapid Progesterone signaling induces meiosis through a dual coreceptor trafficking trap

This study identifies a novel rapid progesterone signaling mechanism in frogs that involves a dual coreceptor trafficking trap to induce meiosis.

Estradiol Modulates Cytotoxic Responses to Topoisomerase II Targeting Agents in Estrogen Receptor Positive Breast Cancer Cells

This study shows estradiol enhances the cytotoxicity of topoisomerase II poisons in ER+ breast cancer cells, suggesting E2-induced cell death relies on TOP2-mediated DNA breaks.