Renal Diseases and Glomerulopathies

This study shows that increased podocyte expression of oligosaccharyltransferase-48kDa subunit worsens diabetic kidney disease by causing endoplasmic reticulum stress and kidney dysfunction.

The paper identifies high-risk nephrotic syndrome patients through transcriptome analysis and develops non-invasive biomarkers to predict disease progression.

The paper identifies shared molecular pathways between ANCA-associated vasculitis and nephrotic syndrome, highlighting JAK-STAT signaling as a potential therapeutic target.

The paper identifies a novel mutation in FAT1 and pathogenic mutations in NPHS2 among SRNS patients, suggesting the need for WES after NPHS2 screening.

The paper investigates the role of APOL1 in PEC phenotype transitions and its interaction with miR193a, showing a feedback loop and its modulation by HIV, IFN-y, and VDA.