Author

Pravin C. Singhal

Feinstein Institute for Medical ResearchORCID 0000-0002-6898-358XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Aakriti Chaturvedi· 1 shared Anil Kumar Ram· 1 shared Anubhav ChakrabortyiD· 1 shared Ashwani Malhotra· 1 shared Catherine Meyer‐SchwesingeriD· 1 shared Frank C. Abbruscato· 1 shared Henrietta EhirimiD· 1 shared Himanshu VashisthaiD· 1 shared

Activity by Year

2018-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperMolecular Biology

Aakriti Chaturvedi

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2 papers

Recent·Most cited

Notch3 deletion regulates HIV-1 gene expression and systemic inflammation to ameliorate chronic kidney disease

Mackenzie M. Thornton, Nicole Sommer, Mercedes B. Mcgonigle, Anil Kumar Ram, Sireesha Yerrathota, Henrietta Ehirim, Aakriti Chaturvedi, Johnny Dinh Phan, Anubhav Chakraborty, Praveen V. Chakravarthi, Sumedha Gunewardena, Mudit Tyagi, Jaya Talreja, Tao Wang, Pravin C. Singhal, , Madhulika Sharma

This study shows that Notch3 deletion reduces HIV-1 gene expression and systemic inflammation, improving outcomes in HIV-associated chronic kidney disease.

Disease Models & Mechanisms · Feb 1, 2025Peer-reviewedMolecular Biology

Apolipoprotein L1 Dynamics in Human Parietal Epithelial Cell Molecular Phenotype Kinetics

Vinod Kumar, Himanshu Vashistha, Xiqian Lan, Nirupama Chandel, Kamesh Ayasolla, Shadafarin Marashi Shoshtari, Rukhsana Aslam, Nitpriya Paliwal, Frank C. Abbruscato, Joanna Mikulak, Waldemar Popik, Ashwani Malhotra, Catherine Meyer‐Schwesinger, Karl L. Skorecki, Pravin C. Singhal

The paper investigates the role of APOL1 in PEC phenotype transitions and its interaction with miR193a, showing a feedback loop and its modulation by HIV, IFN-y, and VDA.

bioRxiv · Feb 4, 2018 · PreprintMolecular Biology