Salivary Gland Tumors Diagnosis and Treatment

Multi-Omic and Spatial Profiling Defines Outcome-Associated Tumor States in Head and Neck Adenoid Cystic Carcinoma

The paper integrates multi-omic and spatial data from HNACC tumors to identify outcome-associated tumor states, finding that aggressive tumors adopt a MYC/E2F-driven luminal state and develop a four-gene classifier for survival prediction.

Functionalized nanoparticle transforms cold to hot adenoid cystic carcinoma of salivary gland tumour microenvironment in vitro

The paper demonstrates that overexpressing ANXA3 in ACC spheroids using functionalized nanoparticles increases tumour infiltrating lymphocytes and reduces spheroid size in vitro.

Gene-Expression Programs in Salivary Gland Adenoid Cystic Carcinoma Analyzed Using Single-Cell and Spatial Transcriptomics

This study uses single-cell and spatial transcriptomics to analyze gene expression in salivary gland adenoid cystic carcinoma, revealing tumor heterogeneity, molecular interactions, and potential therapeutic targets.