Topic · Genetics · Medicine
OpenAlex topic; a paper is listed when OpenAlex scores it at least 0.5 for this topic.
33 papers
Almut Luetge, Junyan Lu, Jennifer Hüllein, Tatjana Walther, Leopold Sellner, Bian Wu, Richard Rosenquist, Christopher C. Oakes, Sascha Dietrich, Wolfgang K. Huber, Thorsten Zenz
This study identifies subgroup-specific gene expression profiles and mixed epistasis in chronic lymphocytic leukemia using RNA-sequencing and genomic data.
bioRxiv · Apr 16, 2021 · PreprintGenomics
Hiba Awadelkareem Osman Fadl, Abdelrahman Hamza Abdelmoneim, Sahar G. Elbager
The paper analyzes CD38 gene SNPs in CLL patients to predict their impact on protein structure and function, identifying 12 deleterious SNPs associated with altered stability and potential functional changes.
bioRxiv · Aug 12, 2020 · PreprintBioinformatics
Jenny Klintman, Basile Stamatopoulos, Kate E. Ridout, Toby Andrew Eyre, L. Lopez Pascua, Niamh Appleby, Samantha J.L. Knight, Helene Marie-Pierre Dreau, Mats Ehinger, José Ignacio Martín-Subero, Elı́as Campo, Robert Månsson, Davide Rossi, Jenny C. Taylor, Dimitris V. Vavoulis, Anna Schuh
The paper identifies genomic and transcriptomic changes in CLL transforming to RS, finding pathway mutations and non-coding mutations in PAX5 enhancers associated with transformation.
HemaSphere · Jun 1, 2019Peer-reviewedGenomics