Advanced Thermodynamics and Statistical Mechanics

Why Life is Hot

The paper shows that cellular chemical reaction networks achieve fitness optimization by coupling to out-of-equilibrium reservoirs, leading to significant heat dissipation, and argues that life is hot due to this mechanism.

A Thermodynamically Consistent Reaction--Diffusion Model of Spatial Proofreading in One and Two Dimensions

This paper develops a thermodynamically consistent reaction-diffusion model to study spatial proofreading in one and two dimensions, showing how energy input, transport, and spatial organization affect molecular discrimination.

State-dependent energy conversion produces degenerate dissipation in active actomyosin networks

The paper shows that energy dissipation in active actomyosin networks depends on mechanical state rather than motor abundance, revealing degenerate dissipation through state-dependent energy conversion.

Bringing calorimetry (back) to life

The paper introduces nonequilibrium calorimetry to study biophysical systems, showing heat capacity can be negative due to biological activity.

Resolving the Brain Energy Paradox: The Neuron as a Coupled Thermodynamic System

This paper develops a coupled electro-thermo-entropic model of action potentials, showing they self-amplify through thermodynamic feedback, leading to an 'Intelligence Premium' in energy cost.

Ecosystems as adaptive living circuits

This paper develops a framework of living circuits using ecosystems as a model, showing that adaptive rules enable phase transitions and near-maximal dissipation in nonequilibrium systems.

Scaling in Biological Systems: A Molecular-Ensemble Duality

The paper presents a statistical analysis showing that molecular and ensemble states evolve with non-scalable entropies, creating a duality that challenges traditional views of irreversibility and the arrow of time.

Biochemical communication with noisy feedback under energy constraints

This paper develops a framework for analyzing information transmission in biochemical reaction networks under energy constraints and derives bounds for reliable communication.