Methanol-specific methyltransferase isozymes have large carbon kinetic isotope effects that impact methane isotopic signatures
Jonathan Gropp, Markus Bill, Daniel A. Stolper, Dipti D. Nayak
This study identifies the methanol-specific methyltransferase complex as the source of large carbon and hydrogen isotope effects in methanol-driven methane production, showing these effects are consistent across isozymes and persist at low methanol concentrations.
Applied and Environmental Microbiology · Jul 21, 2026Peer-reviewedMicrobiology