Topic · Surgery · Medicine

Esophageal and GI Pathology

OpenAlex topic; a paper is listed when OpenAlex scores it at least 0.5 for this topic.

2 papers

Profibrotic Changes Following Tension Application in a Fetal Lamb Model of Long Gap Esophageal Atresia

Jessica C Pollack, Nicolas Vinit, Shelley Jain, Rachel E Conan, Melanie Bates, Mia Kwechin, Alicia L. Eubanks, Mike Xie, Amanda B. Muir, Emily Anne Partridge

This study investigates profibrotic changes in a fetal lamb model of long gap esophageal atresia following tension application, showing increased collagen deposition and TGFB signaling.

bioRxiv · Jan 28, 2026 · PreprintDevelopmental Biology

Identification and validation of novel candidate risk genes in endocytic vesicular trafficking associated with esophageal atresia and tracheoesophageal fistulas

Guojie Zhong, Priyanka R. Ahimaz, Nicole A. Edwards, Jacob Hagen, Christophe C. Faure, Lu Qiao, Paul S. Kingma, William Middlesworth, Julie Khlevner, Mahmoud M. A. Elfiky, David T. Schindel, Elizabeth Fialkowski, Adhish Kashyap, Sophia Forlenza, Alan P. Kenny, , Wendy K. Chung

The paper identifies novel risk genes associated with EA/TEF through whole genome sequencing and functional validation using CRISPR-Cas9 in Xenopus.

Human Genetics and Genomics Advances · Apr 16, 2022Peer-reviewedGenetic & Genomic Medicine