Author

Nicole A. Edwards

Cincinnati Children's Hospital Medical CenterORCID 0000-0001-6952-2569Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 2 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Organism:mouse· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Aaron M. ZorniD· 3 shared Alan P. KennyiD· 3 shared Adhish Kashyap· 2 shared Matthew J. KofroniD· 2 shared Scott A. RankiniD· 2 shared Wendy K. ChungiD· 2 shared Yufeng SheniD· 2 shared Zachary N. Agricola· 2 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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3 shared papersDevelopmental Biology

Aaron M. ZornORCID

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3 papers

Recent·Most cited

Developmental BiologybioRxivPreprintOct 11, 2023

Disrupted endosomal trafficking of the Vangl-Celsr polarity complex underlies congenital anomalies in trachea-esophageal morphogenesis

Nicole A. Edwards, Scott A. Rankin, Adhish Kashyap…·Aaron M. Zorn

The paper shows that disruptions in endosomal trafficking of the Vangl-Celsr polarity complex cause congenital trachea-esophageal malformations in Xenopus, similar to human EA/TEF.

1 citation

mousehuman

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Genetic & Genomic MedicineHuman Genetics and Genomics AdvancesPeer-reviewedApr 16, 2022

Identification and validation of novel candidate risk genes in endocytic vesicular trafficking associated with esophageal atresia and tracheoesophageal fistulas

Guojie Zhong, Priyanka R. Ahimaz, Nicole A. Edwards…·Wendy K. Chung

The paper identifies novel risk genes associated with EA/TEF through whole genome sequencing and functional validation using CRISPR-Cas9 in Xenopus.

14 citations

humanwhole-genome sequencing

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Developmental BiologyDevelopmental CellPeer-reviewedDec 1, 2019

Endosome-Mediated Epithelial Remodeling Downstream of Hedgehog/Gli Is Required for Tracheoesophageal Separation

Talia Nasr, Pamela Mancini, Scott A. Rankin…·Aaron M. Zorn

This paper identifies HH/Gli-dependent cellular mechanisms, including endosome-mediated remodeling and matrix degradation, essential for tracheoesophageal separation in mouse and Xenopus embryos.

49 citations

mousezebrafish

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