Pain Management and Placebo Effect

Hippocampus mediates conceptual generalization of pain modulation

The paper investigates how conceptual generalization influences pain experience and shows that the hippocampus mediates this effect through cue-evoked expectations.

Starting strong: A descending analgesic dosing scheme enhances pain relief compared to a conventional ascending dosing scheme

This study compares descending and ascending analgesic dosing schemes, finding that starting with a high dose enhances placebo-related pain relief compared to starting with a low dose.