Anesthesia and Neurotoxicity Research

Astroglial dysfunctions drive aberrant synaptogenesis in developing brain with lengthy general anesthesia

This study shows that sevoflurane exposure disrupts astrocyte function, leading to synaptic overgrowth and dysfunction in developing brains.

Characterization of DNA hydroxymethylation in hypothalamus of elderly mice with postoperative cognitive dysfunction

This study investigates the impact of sevoflurane on DNA hydroxymethylation and Uhrf2 levels in the hippocampus and amygdaloid nucleus of elderly mice with postoperative cognitive dysfunction.