A Continuum of Atrial Peristalsis Initiates the Bicuspid to Quadricuspid Valve Transition
Jing Wang, Aaron L. Brown, Peng Zhao…·Tzung K. Hsiai
The paper shows that atrial peristalsis drives the transition from a bicuspid to quadricuspid valve in zebrafish through Klf2a-Snai1b signaling and shear stress alignment.