Healthcare and Venom Research

Melittin-induced membrane disruption in hepatocellular carcinoma involves mtROS/GSDME-mediated pyroptosis

This study shows melittin induces pyroptosis in HCC cells via mtROS and GSDME, challenging its traditional view as a membrane-lytic peptide.

The effect of melittin intervention on murine cervical cancer cells: An in-depth proteomics investigation

This study investigates melittin's effects on U14 cervical cancer cells using proteomics, showing inhibition of migration, invasion, and promotion of cell death with significant changes in oxidative stress and mitochondrial pathways.

Deciphering the Effect of Melittin on Murine Cervical Cancer Cells Based on Transcriptomic Investigation

This study investigates melittin's effects on murine cervical cancer cells, showing it inhibits viability, suppresses migration, induces apoptosis, and disrupts metabolic and angiogenic pathways.

Transcriptomic datasets of melittin- and un-treated murine cervical carcinoma U14 cells

The paper generates RNA-seq datasets of melittin-treated and untreated murine cervical carcinoma U14 cells, identifying 254 differentially expressed genes and providing a transcriptomic resource for studying melittin's anti-cancer effects.

Comprehensive transcriptome data of melittin- and un-treated murine hepatoma Hepa 1-6 cells

This paper presents transcriptomic data from melittin-treated and untreated murine hepatoma cells to study melittin's effects on gene expression.

Anastasis induced by bee venom in normal cells compared to persistent cell death in breast cancer cells

This study compares the effects of bee venom and cisplatin on normal and cancer cells, finding bee venom induces anastasis in normal cells but persistent death in cancer cells, with higher selectivity.