Rui Guo

Melittin-induced membrane disruption in hepatocellular carcinoma involves mtROS/GSDME-mediated pyroptosis

This study shows melittin induces pyroptosis in HCC cells via mtROS and GSDME, challenging its traditional view as a membrane-lytic peptide.

The effect of melittin intervention on murine cervical cancer cells: An in-depth proteomics investigation

This study investigates melittin's effects on U14 cervical cancer cells using proteomics, showing inhibition of migration, invasion, and promotion of cell death with significant changes in oxidative stress and mitochondrial pathways.

Deciphering the Effect of Melittin on Murine Cervical Cancer Cells Based on Transcriptomic Investigation

This study investigates melittin's effects on murine cervical cancer cells, showing it inhibits viability, suppresses migration, induces apoptosis, and disrupts metabolic and angiogenic pathways.

Transcriptomic datasets of melittin- and un-treated murine cervical carcinoma U14 cells

The paper generates RNA-seq datasets of melittin-treated and untreated murine cervical carcinoma U14 cells, identifying 254 differentially expressed genes and providing a transcriptomic resource for studying melittin's anti-cancer effects.

Epstein-Barr virus transformation creates a methionine-dependent ferroptosis vulnerability in B cells

This study shows that methionine restriction induces ferroptosis in EBV-transformed B cells by promoting transsulfuration and glutathione synthesis, and that targeting methionine metabolism can impair tumor growth.

Comprehensive transcriptome data of melittin- and un-treated murine hepatoma Hepa 1-6 cells

This paper presents transcriptomic data from melittin-treated and untreated murine hepatoma cells to study melittin's effects on gene expression.

Epstein-Barr Virus Latent Membrane Protein 1 Suppresses Ferroptosis via Pentose Phosphate Pathway and Glutathione Metabolism

This study shows that EBV's LMP1 protein prevents ferroptosis by enhancing glutathione and NADPH through the pentose phosphate pathway and cystine uptake.

A resource for probing influences of perinatal factors on neurodevelopment in 3-10-years-old Chinese children

This paper introduces a multicentre database, periCBD, linking perinatal factors to brain-mind development in children aged 3-10 years to study neurodevelopmental disorders.

Transcriptome-wide characterization of piRNAs during the developmental process of European honey bee larval guts

The paper identifies and analyzes differentially expressed piRNAs in European honey bee larval guts across developmental stages, revealing their potential regulatory roles in development, immunity, and energy metabolism.

Genome-wide identification of long non-coding RNAs and their regulatory networks involved in Apis mellifera ligustica response to Nosema ceranae infection

The paper identifies lncRNAs and their regulatory networks in honeybees responding to Nosema ceranae infection using RNA sequencing and bioinformatics analysis.