Discover, rate, and discuss biology preprints.
363,000+ bioRxiv and medRxiv preprints, including those later published in peer-reviewed journals, across 26 biological disciplines.
Recent preprints
- PhysiologyObesityPeer-reviewed10 citations
- PhysiologyInternational Journal of PsychophysiologyPeer-reviewed
The relevance of accounting for parasympathetic as well as sympathetic arousal in threat conditioning: methodological and clinical considerations
Lars Jaswetz, Lycia D. de Voogd, Eni Sabine Becker, Karin Roelofs
This study examines the role of both parasympathetic and sympathetic arousal in threat conditioning, showing that parasympathetic responses are linked to anxiety resilience and that ignoring them can misclassify individuals as non-learners.
- PhysiologyJournal of Cellular PhysiologyPeer-reviewed
SLO2.1/NALCN Functional Complex Activity in Mouse Myometrial Smooth Muscle Cells During Pregnancy.
Juan José Ferreira, Lindsey N. Kent, Ronald McCarthy…·Celia Maria Santi
This study investigates the role of the SLO2.1/NALCN complex in regulating mouse myometrial smooth muscle cell membrane potential across pregnancy, finding its activity decreases as pregnancy progresses.
6 citations - PhysiologyProceedings of the Royal Society B Biological SciencesPeer-reviewed
Olfactory performance explains duality of antennal architectural designs in Lepidoptera
Mourad Jaffar‐Bandjee, Thomas Engels, Thomas Steinmann…·Jérôme Casas
The paper compares the olfactory performance of pectinate and filiform antennae in Lepidoptera, finding that pectinate antennae are more efficient at capturing odor at most speeds, while filiform are more energy-efficient at low speeds.
- PhysiologyPhysiological ReportsPeer-reviewed
Application of 2H2O to quantify red blood cell protein synthesis rates in young trained and untrained males and females
Hilkka Kontro, Chris McGlory, Martin J. MacInnis
This study measures hemoglobin fractional synthetic rate in trained and untrained humans using 2H2O and finds no difference between trained and untrained individuals or between males and females.
DOI 10.14814/phy2.70311 - PhysiologyPhysiological ReportsPeer-reviewed
Effect of Emoji on Autonomic Nervous System: Evidence from EDA and RSA studies
Deeksha Patel, Abhinav Dixit, Om Lata Bhagat
This study examines how emojis affect autonomic responses, finding increased sympathetic activity and decreased parasympathetic activity in both males and females during an emotional task.
DOI 10.14814/phy2.70225 - PhysiologyFrontiers in PhysiologyPeer-reviewed
A novel method for tracking nitrogen kinetics in vivo and ex vivo using radioactive nitrogen-13 gas and Positron Emission Tomography
Edward Tom Ashworth, Ryotaro Ogawa, David R. Vera, Peter Lindholm
This study develops a PET-based method to track nitrogen gas movement in vivo and ex vivo using 13N2, showing its distribution in organs after inhalation.
- PhysiologyeLifePeer-reviewed
Peripheral opioid receptor antagonism alleviates fentanyl-induced cardiorespiratory depression and is devoid of aversive behavior
Brian C. Ruyle, Sarah Masud, Rohith Kesaraju…·José A. Morón
This study shows that peripheral opioid receptor antagonism can reverse fentanyl-induced respiratory depression without causing aversive behaviors.
11 citations - PhysiologyPhysiological ReportsPeer-reviewed
Effects of Exercise Frequency on Aortic Calcification in Hyperlipidemic Mice
Nora Safvati, Sophia Kalanski, Andy Hon…·Yin Tintut
This study examines the effect of exercise frequency on aortic calcification in hyperlipidemic mice, finding that 5 days/week low-speed treadmill exercise reduces 18F-NaF uptake and cardiac remodeling.
- PhysiologyJournal of Cachexia Sarcopenia and MusclePeer-reviewed
Housing temperature dictates the systemic and tissue specific molecular responses to cancer in mice
Andrea Irazoki, Emma Frank, Tang Cam Phung Pham…·Lykke Sylow
This study shows that housing temperature affects molecular and systemic responses to cancer in mice, influencing metabolic adaptations and cytokine levels.
9 citationstop 4% - PhysiologyThe Journal of PhysiologyPeer-reviewed
Endurance Exercise Elevates Plasma Mature Brain-Derived Neurotrophic Factor through Child- and Adulthood, with Amplified Effects in Adults
Sebastian Edman, Julia Starck, Linnéa Corell…·Ferdinand von Walden
This study shows that endurance exercise increases plasma mature BDNF (mBDNF) in children, adolescents, and adults, with a greater response in adults, and that regular vigorous activity in youth correlates with higher basal mBDNF levels.
13 citationstop 4% - PhysiologyRoyal Society Open SciencePeer-reviewed
Matching dynamically varying forces with multi-motor-unit muscle models: A simulation study
Tiina Murtola, Christopher T. Richards
This study simulates how different motor unit pool models affect force generation in muscles during static and dynamic tasks, finding that feedback improves performance, especially for physiologically relevant models.
2 citations - PhysiologyPlant Growth RegulationPeer-reviewed
Exploration of the intricacies of low light-induced changes in cigar tobacco leaf anticlinal growth: A holistic approach from anatomical and hormonal levels to gene expression
Xinghua Ma, Jinpeng Yang, Xiaochun Ren…·Rayyan Khan
This study examines how low light affects cigar tobacco leaf morphology, growth rates, and gene expression, revealing hormonal and cellular changes in leaf structure.
6 citations - PhysiologyEuropean Journal of NeurosciencePeer-reviewed
Age-related Facilitation of Bimanual Finger Behaviors by Haptic Augmentation
Matti Itkonen, Niko Lappalainen, Hana Vrzáková, Roman Bednarik
This study investigates if haptic augmentation improves bimanual finger response times in middle-aged adults, finding performance gains but not in younger adults.
DOI 10.1111/ejn.70102 - PhysiologyRedox BiologyPeer-reviewed
Oxidative Injury to Lung Mitochondrial DNA is a Key Contributorfor the Development of Chemical Lung Injury
Shubham Dubey, Zhihong Yu, Emily Morgan Stephens…·Sadis Matalon
This study shows that oxidative injury to mitochondrial DNA contributes to acute and chronic lung injury, and that targeting OGG1 can mitigate this damage.
14 citations - PhysiologyHearing ResearchPeer-reviewed
ABRpresto: An algorithm for automatic thresholding of the Auditory Brainstem Response using resampled cross-correlation across subaverages
Luke A. Shaheen, Brad N. Buran, Kirupa Suthakar…·Yoojin Chung
ABRpresto automatically estimates ABR thresholds using resampled cross-correlation across subaverages, achieving 92% accuracy within ±10 dB of human ratings on mouse data.
14 citationstop 2% - PhysiologyLaboratory AnimalsPeer-reviewed
Seasonality of the estrus cycle in laboratory mice under constant conditions
Tess M. Reichard, Caitlin H. Miller, Jay Yang, Michael J. Sheehan
This study shows that female C57BL/6J mice exhibit reproductive seasonality in controlled lab conditions, mirroring external seasonal patterns.
5 citations - PhysiologyFrontiers in PhysiologyPeer-reviewed
Successful stimulation of myocardial ganglionic plexuses by TAU 20 in the absence of cardiac damage
Shengzhe Li, Jamie Kay, Danya Agha-Jaffar…·Rasheda A. Chowdhury
The paper tests a neural simulator, Tau-20 version 2, to safely deliver high-frequency stimulation for identifying ganglionated plexuses in atrial fibrillation treatment without causing cardiac damage.
DOI 10.3389/fphys.2025.1536362 - PhysiologyJournal of the American Society of NephrologyPeer-reviewed
Prothrombin Knockdown Protects Podocytes and Reduces Proteinuria in Glomerular Disease
Amanda P. Waller, Katelyn J. Wolfgang, Iva Pruner…·Bryce A. Kerlin
This study shows that reducing prothrombin levels protects podocytes and decreases proteinuria in a rat model of glomerular disease.
5 citations