Sebastian Edman

This study identifies a distinct cardiometabolic profile and reduced physiological response to exercise in adults with cerebral palsy compared to typically developing individuals.

The paper shows that transient MYC activation in skeletal muscle mimics exercise-induced adaptations, leading to hypertrophy, metabolic changes, and fiber type shifts.

This study shows antioxidant supplementation reduces proteome changes in type 2 muscle fibers during sprint interval training, but not performance improvements.

This study shows that endurance exercise increases plasma mature BDNF (mBDNF) in children, adolescents, and adults, with a greater response in adults, and that regular vigorous activity in youth correlates with higher basal mBDNF levels.

This study examines how endurance exercise with reduced muscle glycogen affects substrate utilization and signaling in human muscle fibers, finding altered fatty acid metabolism and mTORC1-autophagy dynamics.

This study shows that lean, healthy older men maintain anabolic sensitivity to amino acids and exercise, with increased mTORC1 signaling and muscle protein synthesis, suggesting aging alone does not cause anabolic resistance.

This study maps the 24-hour molecular response to resistance exercise in human muscle, identifying MYC as a key regulator of hypertrophy and mRNA levels.