Celia Maria Santi

This study shows that mitochondrial calcium uptake via CatSper and MCU is essential for hyperactivated motility during human sperm capacitation, similar to mouse sperm.

This study identifies TMC5 as essential for mechanoresponsive calcium entry during spermiogenesis, linking mechanical cues to sperm development and male infertility.

This study shows AVP activates AVPR1A in myometrial cells, inhibits SLO2.1 potassium channels, depolarizes cells, and enhances Ca²⁺ entry, increasing excitability and contraction.

This study identifies how CatSper channels integrate temperature and pH signals through structural and evolutionary analyses in sperm.

This study shows that bacterial vaginosis toxins impair sperm capacitation and fertilization by disrupting calcium homeostasis and motility.

This study investigates the role of the SLO2.1/NALCN complex in regulating mouse myometrial smooth muscle cell membrane potential across pregnancy, finding its activity decreases as pregnancy progresses.

This study identifies Na+/H+ exchangers as key regulators of plasma membrane hyperpolarization in mouse sperm, challenging the role of PKA and revealing a novel pathway involving cAMP, calcium, and SLO3 K+ channels.