José A. Morón

This study shows that object-based environmental enrichment reduces fentanyl intake and stress-induced relapse in rats, suggesting it could be a scalable intervention for opioid use and relapse prevention.

This study shows that Cnih3 deletion in mice impairs spatial memory, reward-cue association, and fentanyl self-administration, with potential sex-specific effects on opioid use.

This study shows that inflammatory pain in mice alters sleep architecture and circadian rhythms, with effects dependent on the light cycle.

This study shows that peripheral opioid receptor antagonism can reverse fentanyl-induced respiratory depression without causing aversive behaviors.

The paper introduces an implantable device that autonomously detects and treats opioid overdose, improving survival rates by delivering naloxone and alerting first responders.

The paper shows that pain increases fentanyl self-administration in male rats through time-dependent changes in ventral tegmental area dopamine neuron activity.

The paper demonstrates that activation of dorsal hippocampus to nucleus accumbens projections drives reinforcement via dynorphin neuron activity in the nucleus accumbens.

The paper profiles hippocampal transcriptomes across estrous cycles in mice, identifies estrous-responsive genes, and shows Cnih3 deletion disrupts estrous-specific gene expression patterns.

This study investigates the role of CNIH3 in spatial memory, finding sex-specific effects where CNIH3 deficiency impairs spatial memory in female mice but not males.

This study identifies an endogenous opioid circuit in mice that regulates appetitive behavior through a dorsal raphe to nucleus accumbens projection.

This study shows ethanol induces CPP or CPA via intra-VTA administration, with dose-dependent effects and MOR involvement, and alters NMDA receptor subunit expression in NAc and Hippocampus.

This study examines hippocampal activity during contextual reward association in virtual reality, finding distinct neural encoding for natural and morphine rewards.